Skip to content

Suboxone

The Complete Suboxone Dosage Guide

How Suboxone doses are set for starting and maintenance, the 4 to 24 mg range in the label, why doses differ, and why only your provider should change yours.

Medically reviewed by Daniel R. Karlin, MD, MA, Chief Medical OfficerPubMedGoogle Scholar

Updated October 12, 20265 min read

Measuring cups lined up from largest to smallest on a shelf.

The right Suboxone dose is the one your clinician determines will control opioid withdrawal and cravings while supporting daily functioning and keeping side effects manageable. The film label describes a general maintenance range of 4 mg/1 mg to 24 mg/6 mg daily. Your own dose cannot be worked out reliably from an online chart alone. FDA Suboxone prescribing information

Whether you or your loved one is living with opioid use disorder, it might feel like you're trapped, and there's no way out. The good news is that there's hope. This guide explains how Suboxone is taken and how doses are set.

How To Take Suboxone

Suboxone is used to control opioid withdrawal and cravings. It comes as a film or tablet that dissolves in the mouth.

Use the film whole and let it dissolve in the place in your mouth your prescriber tells you, under the tongue or inside the cheek. Do not cut, chew, or swallow it whole. Take it on the schedule your prescriber sets.

Pick up one film at the outer edges to place it. If your dose uses more than one film, follow your prescriber's and pharmacist's instructions on where to place them. The number of films is not the same as the number of doses.

Before beginning, it's a good idea to drink water first. You'll want to wet the inside of your mouth, at the least.

Do not eat or drink until the medicine has dissolved. It needs to dissolve in your mouth to work as intended.

After it dissolves, gently rinse with water and swallow. Wait at least one hour before brushing your teeth, and keep up regular dental care. FDA: Dental care with buprenorphine

Dosing Suboxone

Suboxone contains buprenorphine and naloxone. A strength written as 8 mg/2 mg means 8 mg of buprenorphine and 2 mg of naloxone in that unit.

Your dosing plan can vary depending on several factors. It will depend on your withdrawal symptoms, the opioids used, and how often you used them.

If you're just starting out, you may go through more than one stage. Starting treatment, adjusting an established prescription, and restarting after a gap are different situations, and each needs clinical guidance. Ask for clear instructions, contact details for problems, and a follow-up plan before the first dose. Do not use someone else's schedule.

Once treatment is established, your clinician reviews withdrawal, cravings, any other opioid use, side effects and how you are functioning, and adjusts the dose in response.

The film label describes a general maintenance range of 4 mg/1 mg to 24 mg/6 mg daily, while recognizing that higher buprenorphine doses may be appropriate for some patients. FDA Suboxone prescribing information

Is 24 mg an absolute maximum? No. FDA has clarified that 16 mg or 24 mg should not be interpreted as universal maximum daily doses. Doses above 24 mg may be appropriate for some patients based on individual needs. That does not mean more is automatically better. FDA: Individualized buprenorphine maintenance doses

Dosage for Those on Heroin

If you're dependent on short-acting opioids or heroin, you might be prescribed Suboxone sublingual film. Standard initiation uses clinical evidence of withdrawal along with your history of opioid use.

A fixed wait of a certain number of hours is not reliable for every person, especially after fentanyl. Your clinician decides when you take the first dose and adjusts the dose based on how you respond.

Dosage for Those on Methadone

If you're dependent on long-acting opioids or methadone, you might be more susceptible to withdrawal during induction. Naloxone/buprenorphine products haven't been evaluated in well-controlled studies for those on long-acting products.

Some patients need a different clinician-directed approach to starting. Follow all instructions from your doctor, who will plan the change with you.

Stopping Treatment

There is no mandatory end date for effective medication treatment. If tapering is considered, it should be gradual, individualized, and paired with follow-up and overdose prevention. CDC: Treating opioid use disorder

Do not stop on your own. Stopping suddenly can bring on opioid withdrawal signs and symptoms.

Suboxone Side Effects

Contact your doctor if you experience side effects. These can include constipation, nausea, and excessive tiredness.

If you have difficulty breathing, get medical care immediately. Severe sedation or abnormal breathing is an emergency requiring 911 and naloxone if available. CDC: Responding to an overdose

Improper Suboxone Use

Never inject, snort, or smoke Suboxone. This can be dangerous. Buprenorphine reduces opioid withdrawal symptoms and cravings when it is taken as prescribed.

In Suboxone, naloxone is added to discourage certain forms of misuse. FDA Suboxone prescribing information

Risks of misuse could include:

  • Overdose
  • Injection-site infections
  • Sepsis
  • Cellulitis
  • Unresponsiveness
  • Cardiorespiratory failure
  • Death

When Should I Take Suboxone?

Your clinician times the first dose, based on signs of withdrawal and the opioids you have been using.

Taking it too early could cause worse symptoms of withdrawal. This is called precipitated withdrawal, and it can happen if you still have other opioids in your system. These symptoms could include an increased heart rate, sweating, and nausea.

Can I Take More if I Still Experience Symptoms?

No. Never take more than prescribed. A change in dose needs approval from your doctor.

Report persistent withdrawal or cravings, missed doses, or a return to other opioids. Do not double doses or restart after an interruption without checking the plan.

Who Sets Suboxone Dosing Guidelines?

Your prescriber sets your dose, working from the FDA-approved prescribing information for the product. FDA Suboxone prescribing information

The federal X-waiver (the DATA 2000 waiver) and its patient limits ended in January 2023. SAMHSA: Waiver elimination

Communication Is Important

Pay attention to the signs and symptoms you experience while on the medication. Consider group or individual counseling with an outside provider to help you through this time.

If you don't feel right on the medication, you might need an adjustment to the dosage. Telling your prescriber early can help you avoid more serious problems.

A Suboxone Dosage Guide

After exploring this guide, you should better understand how a Suboxone dose is set. Different products can absorb differently, so do not substitute strengths or formulations without checking with your prescriber and pharmacist.

A visit with your doctor is the way to find out what dose is right for you.

Start Suboxone treatment online. Recovery Delivered's online Suboxone doctors see patients by video. The first visit is $89. Follow-up visits are $50 weekly, $75 every two weeks or $89 monthly. Visits are cash pay, and medication is priced separately.

Loading this audio summary connects your browser to Recast (app.letsrecast.ai).